Redox regulation of cardiomyocyte proliferation: The Ucp2 Avenue
نویسندگان
چکیده
منابع مشابه
Redox mechanisms of cardiomyocyte mitochondrial protection
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UCP2 induces metabolic reprogramming to inhibit proliferation of cancer cells
Invalidation of uncoupling protein 2 (Ucp2) increases glucose utilization and proliferation in normal cells. We recently reported that cancer cells that overexpress UCP2 become less tumorigenic while switching their metabolism from glycolysis to oxidative phosphorylation. UCP2 appears to be a key regulator of cellular metabolism with a relevant function against tumorigenesis.
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ژورنال
عنوان ژورنال: Archives of Cardiovascular Diseases Supplements
سال: 2021
ISSN: 1878-6480
DOI: 10.1016/j.acvdsp.2021.04.171